Does first polar body morphology predict oocyte performance during ICSI treatment?
نویسندگان
چکیده
منابع مشابه
Evaluating the Role of First Polar Body Morphology on Rates of Fertilization and Embryo Development in ICSI Cycles
BACKGROUND Recent studies have demonstrated that morphology of the first polar body (1(st)PB) is related to oocyte viability, which can be used as a prognostic tool to predict oocyte performance and pregnancy outcomes in an intracytoplasmic sperm injection (ICSI) program. According to some studies, there is a correlation between oocyte performance and 1(st)PB morphology, while others have not r...
متن کاملOptimal ICSI timing after the first polar body extrusion in in vitro matured human oocytes.
BACKGROUND This study was conducted to investigate the fertilization and embryo development of human oocytes injected at different time intervals after extrusion of the first polar body (PB) following in vitro maturation (IVM) in IVM cycles. Also, we evaluated whether spindle imaging could serve as a tool to determine the optimal ICSI time. METHODS Oocytes were collected from 43 women with po...
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During vertebrate egg maturation, cytokinesis initiates after one pole of the bipolar metaphase I spindle attaches to the oocyte cortex, resulting in the formation of a polar body and the mature egg. It is not known what signal couples the spindle pole positioning to polar body formation. We approached this question by drawing an analogy to mitotic exit in budding yeast, as asymmetric spindle a...
متن کاملBody mass index is negatively correlated with the response to controlled ovarian stimulation but does not influence oocyte morphology in ICSI cycles.
OBJECTIVE To investigate whether or not body mass index (BMI) is associated with oocyte dysmorphisms. STUDY DESIGN This retrospective study enrolled 1105 patients undergoing intracytoplasmic sperm injection (ICSI). The correlation between BMI and the response to controlled ovarian stimulation (COS) and ICSI outcomes was analysed. Oocyte morphology was determined in metaphase II (MII) oocytes ...
متن کاملTreatment option for sperm- or oocyte-related fertilization failure: assisted oocyte activation following diagnostic heterologous ICSI.
BACKGROUND Failed fertilization occurs in 2-3% of ICSI cycles and is mainly due to lack of oocyte activation. Heterologous ICSI of patient's sperm in mouse oocytes allows discrimination between sperm- and oocyte-related aetiologies of activation failure. Assisted oocyte activation (AOA) by Ca-ionophore treatment can initiate fertilization in subsequent therapeutic ICSI. We report on diagnosis a...
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ژورنال
عنوان ژورنال: Journal of Assisted Reproduction and Genetics
سال: 2009
ISSN: 1058-0468,1573-7330
DOI: 10.1007/s10815-009-9368-9